Articles Tagged With:
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Infectious Disease Updates
Two-Step Testing for Anal Cancer Screening in HIV; Reducing Complications of PICCs; Plan for the Lifecycle of a PICC
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Diphtheria Surge in Europe
A marked increase in cases of diphtheria in Europe is related to migrants, most often from Syria or Afghanistan, indicating a need to maintain high levels of immunity through vaccination, not only in Europe but everywhere, including the United States.
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Pemivibart for COVID-19 Prophylaxis: Clinical Trial Confirms its Efficacy
Confirming the results of the immunobridging analysis that led to its initial authorization for emergency use, this study demonstrates that pemivibart is effective as prophylaxis against COVID-19, including in immunocompromised patients.
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What Is New with Leptospirosis?
Leptospirosis continues to cause seasonal problems in some urban areas, especially those with large populations of rats and imperfect garbage handling. New diagnostic tests are being developed, and plasma exchange offers the potential of improved outcomes for patients with leptospirosis accompanied by severe pulmonary hemorrhage.
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Patients Hospitalized for Nonsevere COVID-19: No Benefit of CAP Antibiotics
A large population-based, retrospective, cohort study found there was no benefit for antibiotics targeting community-acquired pneumonia in patients hospitalized with nonsevere COVID-19. These results provide evidence against antibiotic use in this population.
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Early Preoperative Antibiotics Before Appendectomy
Pre-incision treatment did not reduce intra-operative perforation, and likewise did not change purulent contamination, peri-appendicular abscess, or histologic gangrene. It did lower 30-day surgical-site infection (SSI) (1.6% vs. 3.2%; P = 0.03) and re-intervention for SSI (0.3% vs. 1.1%), but the effect was marginally significant, giving a number-needed-to-treat of 63 for any SSI and 125 for a re-intervention.
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The RSV Turning Point: Implementing Preventive Tools in Everyday Practice
Respiratory syncytial virus (RSV) causes significant morbidity in infants and older adults. This review outlines new preventive measures, including RSV vaccines for pregnant women and older adults, and monoclonal antibody prophylaxis (nirsevimab) for infants. Clinical guidance addresses patient concerns, administration timing, and indications by age and risk. With these tools, primary care providers can better prevent RSV complications across vulnerable populations.
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Pediatric Abdominal Trauma
Abdominal trauma is a common occurrence, and acute care clinicians must be familiar with the evaluation and management of children with potential abdominal injuries. The authors provide a comprehensive diagnostic and therapeutic approach to this population with the goal of optimizing their outcome.
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An Approach to Palliative Care in the Emergency Department
Emergency physicians play a critical role in recognizing the need for and initiating early palliative care interventions, often at the most pivotal moments in a patient’s illness. By addressing symptoms such as dyspnea, pain, nausea, and constipation early and effectively, and by guiding conversations around goals of care, emergency providers can greatly enhance the quality of life for patients with serious or terminal illnesses.
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Homelessness Raises Unique Ethical Concerns on End-of-Life Care
Homelessness complicates end-of-life care because of isolation, surrogate scarcity, and structural barriers. Ethicists should collaborate with interprofessional teams to ensure respectful, context-aware care and advocate for inclusive policies addressing this vulnerable population’s needs.